Cytokeratin 19 Protéine

N° du produit ABIN1880333

Détail du produit

Antigène: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Type de proteíne: Native

Origine: Humain

Source: Human

Purification: Purified

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Tris-HCl (pH 7.4 +/- 0.2) with 0.2 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C

Détail du antigène

Antigène: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Autre désignation: Cytokeratin 19 (KRT19 Produits)

Synonymes: CK19 Protein, K19 Protein, K1CS Protein, AI663979 Protein, EndoC Protein, Krt-1.19 Protein, Krt1-19 Protein, Ka19 Protein, k19 Protein, ck19 Protein, k1cs Protein, krt9 Protein, krt15 Protein, MGC76282 Protein, GK-19 Protein, MGC83069 Protein, KRT19 Protein, keratin 19 Protein, keratin 19 L homeolog Protein, keratin, type I cytoskeletal 19 Protein, KRT19 Protein, Krt19 Protein, krt19 Protein, krt19.L Protein, LOC100344434 Protein, LOC101117946 Protein

Sujet: Cytokeratin 19 (CK19) belongs to a family of keratins, which are normally expressed in the lining of the gastroenteropancreatic and hepatobiliary tracts. It has been shown to be an independent prognostic factor for pancreatic neuroendocrine tumors, especially the insulin-negative tumors. CK19 positive tumors are associated with poor outcome irrespective of the established pathologic parameters such as size, mitoses, lymphovascular invasion, and necrosis. The low-molecular-weight cytokeratin (CK) protein CK19 has been shown to have diagnostic use and prognostic significance in some types of human malignancy. Cytokeratin-19 alone and its combinations with other markers were more sensitive in accurate diagnosis of papillary carcinoma than the other combinations.