Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

PRSS2 Protéine

PRSS2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 96 % by SDS-PAGE
N° du produit ABIN1880447
  • Antigène Voir toutes PRSS2 Protéines
    PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))
    Type de proteíne
    Recombinant
    Origine
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 3
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Pureté
    > 96 % by SDS-PAGE
    Top Product
    Discover our top product PRSS2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Tris-HCl (pH 7.4 +/- 0.2) with 0.02 % NaN3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Stock
    4 °C
  • Antigène
    PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))
    Autre désignation
    Trypsinogen 2 (PRSS2 Produits)
    Synonymes
    Dvir\\GJ21501 Protein, Dvtry-2 Protein, GJ21501 Protein, Try2 Protein, dvir_GLEANR_6854 Protein, TRY8 Protein, TRYP Protein, Ta Protein, Tesp4 Protein, Ptryss2 Protein, TRY2 Protein, TRYP2 Protein, trypsin-2 Protein, Trypsin-2 Protein, protease, serine 2 Protein, protease, serine, 2 Protein, trypsin II Protein, CpipJ_CPIJ000771 Protein, CpipJ_CPIJ020109 Protein, Dvir\Try2 Protein, Prss2 Protein, PRSS2 Protein, trp-ii Protein
    Sujet
    Trypsinogen is the precursor form or zymogen of the pancreatic enzyme trypsin. It functions as storage of an inactive form of trypsin so that it may be kept in pancreas and released in significant amount when required for protein digestion. Rowen et al. (1996) found that only 2 of 3 pancreatically expressed trypsinogen cDNAs correspond to trypsinogen genes in the TCRB locus, T4 was denoted trypsinogen 1 and T8 was denoted trypsinogen 2. The third pancreatic cDNA, identified independently as trypsinogen 3 and 4, is distinct from the third apparently functional trypsinogen gene (T6) in the TCRB locus but related to the other pancreatic trypsinogens. Teich et al. (2004) demonstrated that the E79K mutation in PRSS1 activated anionic trypsinogen 2-fold better than wildtype cationic trypsin did, whereas the common pancreatitis-associated mutants R122H and N29I had no such effect. The observations not only suggested a novel mechanism of action for pancreatitis-associated trypsinogen mutations, but also highlighted the importance of interactions between the 2 major trypsinogen isoforms in the development of genetically determined chronic pancreatitis.
    Poids moléculaire
    31 kDa
Vous êtes ici:
Support technique