Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP2/FKBP2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala22-Leu142) of Human FKBP2 fused with a polyhistidine tag at the C-terminus.
Pureté
> 95 % as determined by reducing SDS-PAGE.
Stérilité
0.2 μm filtered
niveau d'endotoxine
Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
FKBP2
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
Restrictions
For Research Use only
Format
Liquid
Reconstitution
It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Buffer
Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150mm NaCl, pH 7.5.
Conseil sur la manipulation
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
Stock
-80 °C
Stockage commentaire
Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
FKBP-13 Protein, PPIase Protein, FKBP12 Protein, Fkbp2 Protein, 13kDa Protein, FKBP-2 Protein, mFKBP13 Protein, mFKBP2 Protein, RGD1560660 Protein, zgc:101826 Protein, FK506 binding protein 2 Protein, FK506 binding protein 1a Protein, FK506 binding protein 2 L homeolog Protein, FKBP2 Protein, Fkbp1a Protein, Fkbp2 Protein, fkbp2 Protein, fkbp2.L Protein
Sub Type
Fusionprotein
Sujet
Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. It contains 1 PPIase FKBP-type domain and belongs to the FKBP-type PPIase family, FKBP2 subfamily which takes part in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP2 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 functions as an ER chaperone and as a component of membrane cytoskeletal scaffolds. Alternative Names: Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein.