Amphiregulin Protein (AREG) (AA 101-198)
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- Antigène Voir toutes Amphiregulin (AREG) Protéines
- Amphiregulin (AREG)
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 101-198
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Origine
- Humain
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Source
- HEK-293T Cells
- Attributs du produit
- ED50 < 0.2 ng/mL, measured in a cell proliferation assay using 3T3 cells.
- Pureté
- > 95 % as analyzed by SDS-PAGE.
- niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product AREG Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Stock
- -80 °C
- Stockage commentaire
- Lyophilized recombinant Human Amphiregulin remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Amphiregulin should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- Amphiregulin (AREG)
- Autre désignation
- Amphiregulin (AREG Produits)
- Synonymes
- AR Protein, CRDGF Protein, SDGF Protein, Sdgf Protein, AREG Protein, AREGB Protein, AREG/SDGF Protein, amphiregulin Protein, AREG Protein, Areg Protein
- Sujet
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Amphiregulin is a member of the EGF family of cytokines, which comprises at least ten proteins including EGF, TGF-alpha, HB-EGF, Epiregulin, Tomoregulin, Neuregulins and the various heregulins. Through the EGF/TGF-alpha receptor, it stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin's extracellular domain is proteolytically processed to release the mature protein.
Synonyms: AR, AREG, Colorectum cell-derived growth factor (CRDGF) - Poids moléculaire
- 15-20 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q5U026
- Pathways
- Signalisation RTK, EGFR Signaling Pathway
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