Betacellulin Protein (BTC) (AA 32-111)
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- Antigène Voir toutes Betacellulin (BTC) Protéines
- Betacellulin (BTC)
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 32-111
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Origine
- Souris
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Source
- HEK-293T Cells
- Attributs du produit
- ED50 <0.08 ng/mL, measured in a cell proliferation assay using 3T3 cells.
- Pureté
- > 95 % as analyzed by SDS-PAGE and HPLC.
- niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product BTC Protéine
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Betacellulin (BTC) (AA 32-111) protein (His tag)
BTC Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Betacellulin (BTC) (AA 70-178) protein (GST tag)BTC Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Betacellulin (BTC) (AA 32-111) protein (Fc Tag)BTC Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Betacellulin (BTC) (AA 32-118) protein (His tag)BTC Origine: Humain Hôte: Levure Recombinant > 90 % ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Stock
- -80 °C
- Stockage commentaire
- Lyophilized recombinant murine Betacellulin remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Murine Betacellulin should be stable up to 1 week at 4°C or up to 2 months at -20°C.
- Date de péremption
- 6 months
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- Antigène
- Betacellulin (BTC)
- Autre désignation
- Betacellulin (BTC Produits)
- Synonymes
- BTC Protein, LOC100228121 Protein, probetacellulin Protein, Bcn Protein, betacellulin Protein, betacellulin, epidermal growth factor family member Protein, BTC Protein, LOC100228121 Protein, Btc Protein
- Sujet
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Betacellulin, also known as BTC, belongs to the EGF family of growth factors. It is expressed in many tissues, such as kidney, pancreas and small intestine. Betacellulin is initially synthesized as a membrane-bound precursor containing multiple EGF-like domains in its extracellular region, and is released from the membrane by proteolytic cleavage. BTC is the ligand for EGFR/ErbB receptor tyrosine kinases, and plays a role in cell growth and differentiation. BTC has been reported to promote beta cell growth and differentiation in the pancreas. Pancreas-specific expression of this gene may induce islet neogenesis and remediate hyperglycemia in type I diabetes.
Synonyms: BTC - Poids moléculaire
- 19-24 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q543J8
- Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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