FGF4 Protein (AA 31-206)

N° du produit ABIN2017822

Détail du produit

Antigène: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 31-206

Origine: Humain

Source: Escherichia coli (E. coli)

Attributs du produit: ED50<0.5 ng/mL, measured in a cell proliferation assay using 3T3 cells, corresponding to a specific activity of >2.0× 10^6 units/mg
AA 31-206, expressed with an N-terminal Met.

Pureté: > 95 % by SDS-PAGE and HPLC analyses.

niveau d'endotoxine: < 0.2 EU/μg, determined by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against 50 mM HEPES, 750 mM NaCl, pH 7.5.

Stock: -80 °C

Stockage commentaire: Lyophilized recombinant human Fibroblast Growth Factor-4 (rhFGF-4) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhFGF-4 should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.

Date de péremption: 6 months

Détail du antigène

Antigène: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Autre désignation: Fibroblast Growth Factor-4 (FGF-4) (FGF4 Produits)

Synonymes: HBGF-4 Protein, HST Protein, HST-1 Protein, HSTF1 Protein, K-FGF Protein, KFGF Protein, Fgf-4 Protein, Fgfk Protein, Hst1 Protein, Hstf-1 Protein, KS3 Protein, hst Protein, hst-1 Protein, kFGF Protein, Hst Protein, fibroblast growth factor 4 Protein, FGF4 Protein, Fgf4 Protein

Sujet: Fibroblast Growth Factor-4 (FGF-4) also known as K-FGF is a heparin-binding growth factor of the FGF family.It was identified by its oncogenic transforming activity. FGF-4 and FGF-3 are located closely on chromosome 11. FGF-4 and its receptors (FGF R1c, 2c, 3c and 4) play an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. FGF-4 is required for normal limb and cardiac valve development during embryogenesis. Recombinant human Fibroblast Growth Factor-4 (rhFGF-4) produced in E. coli is a single non-glycosylated polypeptide chain containing 177 amino acids. A fully biologically active molecule obtained by proprietary chromatographic techniques, rhFGF-4 has a molecular mass of 19.4 kDa as analyzed by reducing SDS-PAGE.
Synonyms: HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF.

Poids moléculaire: 19.4kDa, observed by reducing SDS-PAGE.

UniProt: P08620

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance