HA
Origine: Influenza A Virus H3N2
Hôte: Influenza A Virus
Native
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/mL or lower.
Buffer
Lyophilized in 20 mM PB buffer ( pH 7.4), 300 mM NaCl, 5 % mannitol, 5 % trehalose.
Stock
-80 °C
Stockage commentaire
Lyophilized recombinant Influenza A H1N1 (A/California/04/2009(H1N1)) Hemagglutinin remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, HA-H1N1 remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
hemagglutinin Protein, Hemagglutinin Protein, HA Protein, HA Protein, ha Protein
Classe de substances
Influenza Protein
Sujet
Influenza hemagglutinin (HA) is a glycoprotein found on the surface of the influenzavirus. It is responsible for binding the virus to cells with sialic acid on their membranes, such as cells in the upper respiratory tract or erythrocytes. It is also responsible for the fusion of the viral envelope with the endosome membrane after the pH has been reduced. The name hemagglutinin comes from the protein's ability to cause red blood cells (erythrocytes) to clump together in vitro. HA has two functions. First, it allows the recognition of target vertebrate cells, accomplished through binding to these cells' sialic acid-containing receptors. Second, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. H1N1 is a subtype of influenza virus A and the most common cause of influenza in humans. Recombinant Influenza A H1N1 (A/California/04/2009(H1N1)) Hemagglutinin with his-tag produced in Sf9 Cell is a single, glycosylated polypeptide chain containing 520 amino acids. A fully biologically active molecule, HA-H1N1 has a molecular mass of ~66 kDa analyzed by reducing SDS-PAGE. Synonyms: HA