IFNB1 Protein (AA 22-187)
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- Antigène Voir toutes IFNB1 Protéines
- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 22-187
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Origine
- Humain
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Source
- HEK-293T Cells
- Attributs du produit
- ED50 < 0.1 ng/mL, measured in a proliferation assay using TF-1 Cells.
- Pureté
- > 95 % as analyzed by SDS-PAGE.
- niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
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- Discover our top product IFNB1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Stock
- -80 °C
- Stockage commentaire
- Lyophilized recombinant Human Interferon-beta remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interferon-beta should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
- Autre désignation
- Interferon-beta (IFNB1 Produits)
- Synonymes
- IFB Protein, IFF Protein, IFNB Protein, IFN-beta Protein, Ifb Protein, Ifnb Protein, IFNb Protein, interferon beta 1 Protein, interferon beta 1, fibroblast Protein, interferon, beta 1, fibroblast Protein, IFNB1 Protein, Ifnb1 Protein
- Sujet
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Interferon-beta (IFN-beta), acting via STAT1 and STAT2, is known to upregulate and downregulate a wide variety of genes, most of which are involved in the antiviral immune response. It is a member of Type I IFNs, which include IFN-alpha, -beta, tau, and omega. IFN-beta plays an important role in inducing non-specific resistance against a broad range of viral infections. It also affects cell proliferation and modulates immune responses.
Synonyms: Leukocyte interferon, B cell interferon, Type I interferon - Poids moléculaire
- 23 kDa, observed by reducing SDS-PAGE.
- UniProt
- P01574
- Pathways
- Signalistation JAK/STAT, TCR Signaling, Signalisation TLR, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
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