IL-2 Protein (AA 21-153)
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- Antigène Voir toutes IL-2 (IL2) Protéines
- IL-2 (IL2) (Interleukin 2 (IL2))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 21-153
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Origine
- Humain
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Source
- CHO Cells
- Attributs du produit
- ED50 < 2 ng/mL, measured in a cell proliferation assay using CTLL-2 cells.
- Pureté
- > 95 % as analyzed by SDS-PAGE.
- niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL2 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS..
- Stock
- -80 °C
- Stockage commentaire
- Lyophilized recombinant Human Interleukin-2 (IL-2) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interleukin-2 (IL-2) should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- IL-2 (IL2) (Interleukin 2 (IL2))
- Autre désignation
- Interleukin-2 (IL-2) (IL2 Produits)
- Sujet
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Interleukin-2 (IL-2) is a Oglycosylated, four alpha-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, gamma delta T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.
Synonyms: T-cell growth factor (TCGF), Aldesleukin - Poids moléculaire
- 15-16 kDa, observed by reducing SDS-PAGE.
- UniProt
- P60568
- Pathways
- Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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