NGFR Protein (AA 29-250)

N° du produit ABIN2018287

Détail du produit

Antigène: NGFR (Nerve Growth Factor Receptor (NGFR))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 29-250

Origine: Humain

Source: HEK-293T Cells

Attributs du produit: ED50 < 0.4 μg /mL, measured in a neutrolization assay using TF-1 cells in the presence of 10 ng/mL human b-NGF.

Pureté: > 95 % as analyzed by SDS-PAGE.

niveau d'endotoxine: < 0.2 EU/μg, determined by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Stock: -80 °C

Stockage commentaire: Lyophilized recombinant human NGF Receptor remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human NGF Receptor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Date de péremption: 6 months

Détail du antigène

Antigène: NGFR (Nerve Growth Factor Receptor (NGFR))

Autre désignation: NGF Receptor (NGFR Produits)

Synonymes: ngfr Protein, wu:fb38c02 Protein, wu:fc10h01 Protein, CD271 Protein, Gp80-LNGFR Protein, TNFRSF16 Protein, p75(NTR) Protein, p75NTR Protein, LNGFR Protein, RNNGFRR Protein, Tnfrsf16 Protein, p75 Protein, NRH1b Protein, fullback Protein, nrh1 Protein, p75ntr Protein, tnfrsf16 Protein, p75NGFR Protein, nerve growth factor receptor Protein, neurotrophin receptor associated death domain Protein, nerve growth factor receptor S homeolog Protein, nerve growth factor receptor (TNFR superfamily, member 16) Protein, NGFR Protein, nradd Protein, Ngfr Protein, ngfr.S Protein

Sujet: NGF Receptor, also known as Gp80-LNGFR, p75 ICD, CD271 and TNFRSF16, is a type I transmembrane protein belonging to the TNF receptor family. It is expressed by both neuronal and non-neuronal cells. Signaling through NGF Receptor has been shown to regulate gene expression, cell migration and death. A truncated NGF Receptor containing only the extracellular domain has been detected in plasma, amniotic fluid and urine, and acts as a potent NGF antagonist.
Synonyms: Gp80-LNGFR, p75 ICD, CD271, TNFRSF16

Poids moléculaire: 32-60 kDa, observed by reducing SDS-PAGE.

UniProt: P08138

Pathways: Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding