PF4 Protein (AA 32-101)
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- Antigène Voir toutes PF4 Protéines
- PF4 (Platelet Factor 4 (PF4))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 32-101
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Origine
- Humain
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Source
- HEK-293T Cells
- Attributs du produit
- ED50 < 10 μg/mL, measured by its ability to inhibit human FGF-basic-dependent proliferation of NR6R 3T3 mouse fibroblast cells.
- Pureté
- > 95 % as analyzed by SDS-PAGE and HPLC.
- niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
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Platelet Factor 4 (PF4) (AA 30-105) protein (Fc Tag)
PF4 Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Platelet Factor 4 (PF4) (AA 32-101) protein (His-Avi Tag)PF4 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Platelet Factor 4 (PF4) (AA 32-101) protein (His-Avi Tag,Biotin)PF4 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Platelet Factor 4 (PF4) (AA 1-101) protein (GST tag)PF4 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Platelet Factor 4 (PF4) (AA 32-101) protein (Fc Tag)PF4 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Platelet Factor 4 (PF4) (AA 32-101) protein (His tag)PF4 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Platelet Factor 4 (PF4) (AA 34-101) protein (Fc Tag)PF4 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Stock
- -80 °C
- Stockage commentaire
- Lyophilized recombinant human platelet factor 4 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human platelet factor 4 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- PF4 (Platelet Factor 4 (PF4))
- Autre désignation
- Platelet Factor 4/CXCL4 (PF4 Produits)
- Sujet
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Platelet factor 4, also known as CXCL4, is expressed in megakaryocytes and stored in the alpha-granules of platelets. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. Platelet factor 4 can be antiproliferative and antiangiogenic, at least in part via interfering with FGF2 and VEGF heparin binding and thus inhibiting their signaling. However, it can also be proinflammatory and proatherogenic through multiple effects on monocytes, macrophages and endothelial cells.
Synonyms: PF-4, CXCL4, SCYB4,Platelet Factor-4, CXCL4, Oncostatin A, Ironplact - Poids moléculaire
- -7.8 kDa, observed by non-reducing SDS-PAGE.
- UniProt
- P02776
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