TWEAK Protein (AA 99-249)
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- Antigène Voir toutes TWEAK (TNFSF12) Protéines
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 99-249
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Origine
- Humain
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Source
- CHO Cells
- Attributs du produit
- ED50 < 1 ng/mL, measured in a cell cytotoxicity assay using HTB-38 (HT-29) cells.
- Pureté
- > 95 % as analyzed by SDS-PAGE and HPLC.
- niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product TNFSF12 Protéine
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Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 43-249) protein (Fc Tag)
TNFSF12 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 106-249) protein (His-DYKDDDDK-Strep II Tag)TNFSF12 Origine: Humain Hôte: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 49-134) protein (GST tag)TNFSF12 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) (AA 1-134) protein (GST tag)TNFSF12 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Stock
- -80 °C
- Stockage commentaire
- Lyophilized recombinant Human TWEAK remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human TWEAK should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
- Autre désignation
- TWEAK (TNFSF12 Produits)
- Synonymes
- APO3L Protein, DR3LG Protein, TWEAK Protein, Apo3l Protein, Dr3l Protein, Dr3lg Protein, Tweak Protein, TNF superfamily member 12 Protein, tumor necrosis factor (ligand) superfamily, member 12 Protein, TNFSF12 Protein, Tnfsf12 Protein
- Sujet
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TWEAK, short for TNF-related weak inducer of apoptosis, is also known as TNFSF12 and DR3LG. It is a type II transmembrane protein belonging to the TNF superfamily. It is expressed widely in many tissues, such as the heart, skeletal muscle, spleen and peripheral blood. Binding of TWEAK to its receptor TWEAKR induces NF-kappaB activation, chemokine secretion and apoptosis in certain cell types. TWEAK has also been reported to promote endothelial cell proliferation and migration, thus serving as a regulator of angiogenesis.
Synonyms: TNF-related weak inducer of apoptosis, TNFSF12, DR3LG, Apo3-Ligand - Poids moléculaire
- 20-22 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q4ACW9
- Pathways
- Apoptose
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