BCMA (TNFRSF17)
(Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
Type de proteíne
Recombinant
Activité biologique
Active
Attributs du protein
AA 1-54
Origine
Humain
Source
HEK-293 Cells
Purification/Conjugué
Cette BCMA protéine est marqué à la Fc Tag.
Séquence
AA 1-54
Attributs du produit
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32 kDa. As a result of glycosylation, the protein migrates as 35-40 kDa under reducing (R) condition, and 66 kDa under non-reducing (NR) condition (SDS-PAGE).
TNFRSF17
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
ELISA
TNFRSF17
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
Restrictions
For Research Use only
Format
Lyophilized
Buffer
PBS, pH 7.4
Conseil sur la manipulation
Please avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.