BMP2 Protein (AA 284-396)

N° du produit ABIN2180654

Détail du produit

Antigène: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Type de proteíne: Recombinant

Attributs du protein: AA 284-396

Origine: Humain

Source: Escherichia coli (E. coli)

Séquence: AA 284-396

Attributs du produit: This protein carries no "tag". The protein has a calculated MW of 13 kDa. the protein migrates as 13 kDa under reducing (R) condition, and 24 kDa under non-reducing (NR) condition (SDS-PAGE).

Pureté: >92 % as determined by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 100 mM Acetic Acid, pH 2.8

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).

Détail du antigène

Antigène: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Autre désignation: BMP-2 (BMP2 Produits)

Synonymes: BDA2 Protein, BMP2A Protein, AI467020 Protein, Bmp2a Protein, BMP-2 Protein, xBMP-2 Protein, xbmp2 Protein, BMP2 Protein, bmp2a Protein, bmp2 Protein, wu:fc59d09 Protein, bone morphogenetic protein 2 Protein, bone morphogenetic protein 2 L homeolog Protein, Bone morphogenetic protein 2 Protein, bone morphogenetic protein 2a Protein, BMP2 Protein, Bmp2 Protein, bmp2.L Protein, bmp2 Protein, bmp2a Protein

Sujet: Human bone morphogenetic protein 2 (BMP2) is also known as human BMP-2, BMP-2, BMP2, BMP 2, h-BMP-2, rh-BMP-2, recombinant human BMP-2, recombinant BMP-2, BMP, is a member of the BMP subgroup belonging to the TGF-b superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. As implied by its name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types, and induce apoptosis in human myeloma cell lines as a novel function.

Poids moléculaire: 12.8 kDa

NCBI Accession: NP_001191

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation