GDF7 Protéine

N° du produit ABIN2468476

Détail du produit

Antigène: GDF7 (Growth Differentiation Factor 7 (GDF7))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Séquence: TALAGTRTAQ GSGGGAGRGH GRRGRSRCSR KPLHVDFKEL GWDDWIIAPL DYEAYHCEGL CDFPLRSHLE PTNHAIIQTL LNSMAPDAAP ASCCVPARLS PISILYIDAA NNVVYKQYED MVVEACGCR

Attributs du produit: Biological activity was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.

Pureté: < 98 % by SDS-PAGE gel and HPLC analyses.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Conseil sur la manipulation: As with any protein, exposing GDF-7 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Stock: -20 °C

Stockage commentaire: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GDF-7 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Date de péremption: 24 months

Détail du antigène

Antigène: GDF7 (Growth Differentiation Factor 7 (GDF7))

Autre désignation: GDF-7 (GDF7 Produits)

Synonymes: bmp12 Protein, gdf-7 Protein, gdf16 Protein, gdf16-A Protein, BMP12 Protein, GDF6/7 Protein, growth differentiation factor 7 S homeolog Protein, growth differentiation factor 7 Protein, gdf7.S Protein, GDF7 Protein, Gdf7 Protein

Sujet: GDF-7 belongs to the TGF-beta superfamily of growth and differentiation factors. It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissue. Recombinant human GDF-7 is a 28 kDa disulfide linked homodimer containing two 129 amino acid residues.

ID gène: 151449

NCBI Accession: NP_878248

OMIM: 61835232

UniProt: Q7Z4P5

Pathways: Tube Formation