FCER2
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
FCER2
Origine: Humain
Hôte: Wheat germ
Recombinant
AP
Restrictions
For Research Use only
Format
Lyophilized
Conseil sur la manipulation
As with any protein, exposing Soluble CD23 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Stock
-20 °C
Stockage commentaire
The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Soluble CD23 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
Date de péremption
24 months
Antigène
FCER2
(Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
BLAST-2 Protein, CD23 Protein, CD23A Protein, CLEC4J Protein, FCE2 Protein, IGEBF Protein, Fcer2a Protein, Fc fragment of IgE receptor II Protein, FCER2 Protein, Fcer2 Protein
Sujet
CD23, the low affinity receptor for IgE, belongs to the C-type lectin structural family and plays a role in the regulation of IgE synthesis and IgE mediated activities. It is found both as a transmembrane receptor protein and in a soluble form, which is generated by proteolytic cleavage of membrane bound CD23. The predominant soluble form of CD23 (sCD23) consists of 172 amino acids corresponding to the extracellular domain of the full length precursor. sCD23, in addition to binding IgE, also exerts a number of IgE independent activities, such as promoting the activation and differentiation of B-cells and stimulating the release of pro-inflammatory cytokines from monocytes. Recombinant human sCD23 is a 19.2 kDa non-glycosylated protein containing 172 amino-acid residues.