IL-8 Protein (AA 28-99)
-
- Antigène Voir toutes IL-8 (IL8) Protéines
- IL-8 (IL8) (Interleukin 8 (IL8))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 28-99
-
Origine
- Humain
-
Source
- Escherichia coli (E. coli)
- Application
- Western Blotting (WB), Immunofluorescence (IF)
- Pureté
- >98 % , as determined by Coomassie stained SDS-PAGE and HPLC analysis.
- niveau d'endotoxine
-
Less than 0.1 ng per μg of protein.
- Top Product
- Discover our top product IL8 Protéine
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
-
Biological activity: Bioactivity was measured by its property to chemoattract human peripheral blood neutrophils in a dose dependent manner. The chemotactic activity was detected from 10 to 100 ng/ml.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- For maximum results, quick spin vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. It is recommended to further dilute in a buffer, such as 5 % Trehalose, and store working aliquots at -20 °C to -80 °C.
- Buffer
- Lyophilized, carrier-free.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Unopened vial can be stored at -20°C or -70°C.
-
- Antigène
- IL-8 (IL8) (Interleukin 8 (IL8))
- Autre désignation
- IL-8 (IL8 Produits)
- Synonymes
- CXCL8 Protein, GCP-1 Protein, GCP1 Protein, LECT Protein, LUCT Protein, LYNAP Protein, MDNCF Protein, MONAP Protein, NAF Protein, NAP-1 Protein, NAP1 Protein, IL-8 Protein, AMCF-I Protein, il8 Protein, IL8 Protein, si:dkey-151b16.2 Protein, cxcli2 Protein, cxcl8 Protein, gcp-1 Protein, il-8 Protein, lynap Protein, mdncf Protein, monap Protein, nap-1 Protein, C-X-C motif chemokine ligand 8 Protein, interleukin 8 Protein, chemokine (C-X-C motif) ligand 8a Protein, chemokine (C-X-C motif) ligand 1-like Protein, chemokine (C-X-C motif) ligand 8 L homeolog Protein, CXCL8 Protein, il8 Protein, cxcl8a Protein, IL8 Protein, Cxcl8 Protein, LOC422654 Protein, cxcl8.L Protein
- Sujet
- IL-8 (CXCL8) was originally recognized as a neutrophil-activating protein on the basis of two in vitro effects, chemotaxis and the release of granule enzymes. IL-8 is generated as a precursor of 99 amino acids. Once the mature cytokine is secreted, the amino-terminal is processed to yield several biologically active variants. The predominant variant consists of 72 amino acids. IL-8 is one of the ELR (Glu-Leu-Arg) motif-positive CXC-chemokines and shares similarities with angiogenic cytokines.
- Poids moléculaire
- The 72 amino acid recombinant protein has a predicted molecular mass of 8.4 kDa. The predicted N-terminal amino acid is Ser.
- Pathways
- Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
-