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Lamin A/C Protein (LMNA)

LMNA Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS
N° du produit ABIN2669331
  • Antigène Voir toutes Lamin A/C (LMNA) Protéines
    Lamin A/C (LMNA)
    Type de proteíne
    Recombinant
    Origine
    • 5
    • 3
    • 2
    Humain
    Source
    • 6
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    Western Blotting (WB), SDS-PAGE (SDS)
    Attributs du produit
    Recombinant human lamin A is a 645 amino acids protein with a molecular weight of 70 kDa.
    Pureté
    > 90 %
    Top Product
    Discover our top product LMNA Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    20 mM phosphate buffer pH 7.0, 0.5M NaCl, 1 mM DTT, 1.5 mM EDTA, 20 % (v/v) glycerol
    Stock
    -20 °C
  • Antigène
    Lamin A/C (LMNA)
    Autre désignation
    Lamin A (LMNA Produits)
    Synonymes
    CDCD1 Protein, CDDC Protein, CMD1A Protein, CMT2B1 Protein, EMD2 Protein, FPL Protein, FPLD Protein, FPLD2 Protein, HGPS Protein, IDC Protein, LDP1 Protein, LFP Protein, LGMD1B Protein, LMN1 Protein, LMNC Protein, LMNL1 Protein, PRO1 Protein, Dhe Protein, 2459 Protein, 74/76 Protein, CG6944 Protein, D5 Protein, DM[[O]] Protein, Dm Protein, Dm(0) Protein, Dm0 Protein, Dm1 Protein, Dm2 Protein, DmLamin Protein, DmO Protein, Dm[[0]] Protein, Dm[[1]] Protein, Dm[[2]] Protein, Dm[[mit]] Protein, Dm[[o]] Protein, Dmel\\CG6944 Protein, Dmo Protein, LAM Protein, Lam Dm[[0]] Protein, Lam(Dm0) Protein, LamDm[[0]] Protein, LamDm[[o]] Protein, Lam[[Dm0]] Protein, Lamin Dm[[0]] Protein, jf27 Protein, l(2)04643 Protein, l(2)25Ec Protein, l(2)gdh-7 Protein, l(2)gdh7 Protein, l(2)jf27 Protein, lam Protein, lamDm0 Protein, lamDm[[0]] Protein, lamin Protein, lamin Dm0 Protein, lamin Dm[[0]] Protein, misg Protein, nlam Protein, cb948 Protein, fk66d12 Protein, wu:fk66d12 Protein, lmna-A Protein, fpl Protein, idc Protein, lfp Protein, cddc Protein, emd2 Protein, fpld Protein, hgps Protein, ldp1 Protein, lmn1 Protein, lmnc Protein, pro1 Protein, cdcd1 Protein, cmd1a Protein, cmt2b1 Protein, lgmd1b Protein, Lamin-A Protein, lamin-L(III)-like Protein, lamin A/C Protein, lamin A Protein, Lamin Protein, lamin A/C L homeolog Protein, lamin-L(III)-like Protein, LMNA Protein, Lmna Protein, Lam Protein, lmna Protein, lmna.L Protein, LMINA Protein
    Sujet
    Lamin A is a major component of the nuclear lamina, a dynamic meshwork located just under the nuclear envelope and it is encoded by lamin A/C gene (LMNA). Lamin A is synthesized as a longer precursor, prelamin A (code REP0038), that in vivo undergoes to serial post-translational modifications that lead to mature lamin A. Different mutations in the LMNA gene have been associated with different diseases that are collectively called laminophaties, including Emery-Dreifuss muscular dystrophy, familiar partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
    Pathways
    Apoptose, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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