Claudin 1 Protein (CLDN1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2712852

Détail du produit

Antigène: Claudin 1 (CLDN1)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Claudin 1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Claudin-1 / CLDN1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Claudin 1 (CLDN1)

Autre désignation: Claudin-1,cldn1 (CLDN1 Produits)

Synonymes: CLD1 Protein, ILVASC Protein, SEMP1 Protein, AI596271 Protein, cldn19 Protein, claudin-1 Protein, cld1 Protein, ilvasc Protein, semp1 Protein, CLDN1 Protein, claudin 1 Protein, claudin 1 S homeolog Protein, CLDN1 Protein, Cldn1 Protein, cldn1 Protein, cldn1.S Protein

Sujet: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.

Poids moléculaire: 22.6 kDa

NCBI Accession: NP_066924

Pathways: Cell-Cell Junction Organization, Hepatitis C