Factor VII Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2712925

Détail du produit

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Factor VII protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Coagulation factor VII (F7) (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Abstract: F7 Produits

Synonymes: F7 Protein, wu:fb59f04 Protein, zgc:109870 Protein, SPCA Protein, AI114908 Protein, ATIII Protein, At-3 Protein, At3 Protein, LOC100223776 Protein, AI132620 Protein, Cf7 Protein, FVII Protein, mfVII Protein, f7 Protein, coagulation factor VII Protein, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 Protein, coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog Protein, F7 Protein, f7 Protein, Serpinc1 Protein, CpipJ_CPIJ009142 Protein, CpipJ_CPIJ010295 Protein, CpipJ_CPIJ020127 Protein, fa7 Protein, f7.S Protein

Sujet: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.

Poids moléculaire: 28 kDa

NCBI Accession: NP_062562

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling