RCAN1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes RCAN1 Protéines
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette RCAN1 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human Calcipressin-1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RCAN1 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
- Autre désignation
- Calcipressin-1 (RCAN1 Produits)
- Synonymes
- ADAPT78 Protein, CSP1 Protein, DSC1 Protein, DSCR1 Protein, MCIP1 Protein, RCN1 Protein, RCAN1 Protein, 2410048A02Rik Protein, AA408855 Protein, AI429645 Protein, AL024459 Protein, AV028423 Protein, Adapt78 Protein, CALP1L Protein, Dscr1 Protein, Mcip1 Protein, dscr1 Protein, rcan1 Protein, wu:fr92c05 Protein, adapt78 Protein, csp1 Protein, dsc1 Protein, mcip1 Protein, MGC53636 Protein, rcn1 Protein, MGC69428 Protein, regulator of calcineurin 1 Protein, regulator of calcineurin 1b Protein, regulator of calcineurin 1 L homeolog Protein, Down syndrome critical region gene 1 Protein, RCAN1 Protein, Rcan1 Protein, rcan1b Protein, rcan1.L Protein, dscr1 Protein, rcan1 Protein
- Sujet
- The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.
- Poids moléculaire
- 27.9 kDa
- NCBI Accession
- NP_004405
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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