PTPRJ Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes PTPRJ Protéines
- PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette PTPRJ protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human CD148 / PTPRJ (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTPRJ Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- PTPRJ (Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
- Autre désignation
- Cd148,ptprj (PTPRJ Produits)
- Synonymes
- HAAP Protein, CD148 Protein, DEP1 Protein, HPTPeta Protein, R-PTP-ETA Protein, SCC1 Protein, AI450271 Protein, BET Protein, Byp Protein, DEP-1 Protein, PTPbeta2 Protein, Ptpb2 Protein, RPTPJ Protein, Scc-1 Protein, Scc1 Protein, PTPRJ Protein, acid phosphatase 1 Protein, protein tyrosine phosphatase, receptor type J Protein, protein tyrosine phosphatase, receptor type, J Protein, ACP1 Protein, PTPRJ Protein, Ptprj Protein, EUBREC_2762 Protein
- Sujet
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
- 142 kDa
- NCBI Accession
- NP_002834
- Pathways
- EGFR Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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