PLAUR Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes PLAUR Protéines
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette PLAUR protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human CD87 / uPAR (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PLAUR Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixtures." dans: Biophysical journal, Vol. 107, Issue 9, pp. 2101-11, (2014) (PubMed).
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Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixtures." dans: Biophysical journal, Vol. 107, Issue 9, pp. 2101-11, (2014) (PubMed).
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- Antigène
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
- Autre désignation
- Cd87,upar (PLAUR Produits)
- Synonymes
- Cd87 Protein, u-PAR Protein, uPAR Protein, CD87 Protein, U-PAR Protein, UPAR Protein, URKR Protein, Par Protein, Plaur3 Protein, uPAR-2 Protein, uPAR-3 Protein, PLAUR Protein, plasminogen activator, urokinase receptor Protein, Plaur Protein, PLAUR Protein
- Sujet
- This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
- Poids moléculaire
- 34.6 kDa
- NCBI Accession
- NP_002650
- Pathways
- Inositol Metabolic Process
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