CDK8 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes CDK8 Protéines
- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette CDK8 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human CDK8 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CDK8 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
- Autre désignation
- Cdk8 (CDK8 Produits)
- Synonymes
- K35 Protein, wu:fk95h11 Protein, cyclin dependent kinase 8 Protein, cyclin-dependent kinase 8 Protein, cyclin-dependent kinase 8 S homeolog Protein, Cyclin-dependent kinase 8 Protein, cyclin dependent kinase 19 Protein, CDK8 Protein, Cdk8 Protein, cdk8 Protein, cdk8.S Protein, cdk-8 Protein, CDK19 Protein
- Sujet
- This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
- Poids moléculaire
- 53.1 kDa
- NCBI Accession
- NP_001251
- Pathways
- Cycle Cellulaire, Regulation of Lipid Metabolism by PPARalpha
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