EPS15 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes EPS15 Protéines
- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
- Type de proteíne
- Recombinant
- Origine
- Humain
- Source
- HEK-293 Cells
- Purification/Conjugué
- Cette EPS15 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human AF1P / EPS15 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
- Autre désignation
- Af1p,eps15 (EPS15 Produits)
- Synonymes
- AF-1P Protein, AF1P Protein, MLLT5 Protein, CG16932 Protein, Dmel\\CG16932 Protein, EH1 Protein, EPS-15 Protein, Eps15 Protein, anon-WO0118547.85 Protein, eps-15 Protein, eps15 Protein, i31 Protein, 2410112D09Rik Protein, RGD1307641 Protein, epidermal growth factor receptor pathway substrate 15 Protein, Epidermal growth factor receptor pathway substrate clone 15 Protein, hypothetical protein Protein, EPS15 Protein, Eps-15 Protein, eps15 Protein, Eps15 Protein, PGTG_06574 Protein
- Sujet
- This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Poids moléculaire
- 98.5 kDa
- NCBI Accession
- NP_001972
- Pathways
- EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation
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