ALT Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2714525

Détail du produit

Antigène: ALT (Alanine Aminotransferase (ALT))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ALT protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Alanine aminotransferase 1 / ALT1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." dans: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Détail du antigène

Antigène: ALT (Alanine Aminotransferase (ALT))

Autre désignation: Alanine Aminotransferase 1 (Alt1) (ALT Produits)

Synonymes: AAT1 Protein, ALT1 Protein, GPT1 Protein, GPT Protein, Gpt1 Protein, An11g02620 Protein, AO090003000164 Protein, 233.t00009 Protein, 24.t00016 Protein, 1300007J06Rik Protein, 2310022B03Rik Protein, ALT Protein, Gpt-1 Protein, AU021132 Protein, Dpagt2 Protein, Gnpta Protein, gpt Protein, ALANINE AMINOTRANSFERAS Protein, AtAlaAT1 Protein, AtAlaATc Protein, T13M22.3 Protein, T13M22_3 Protein, alanine aminotransferas Protein, glutamic--pyruvic transaminase Protein, glutamic-pyruvate transaminase (alanine aminotransferase) Protein, alanine aminotransferase Protein, alanine aminotransferase 1 Protein, glutamic pyruvic transaminase, soluble Protein, dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) Protein, alanine aminotransferase 2-like Protein, Alanine aminotransferase 1, mitochondrial Protein, GPT Protein, Gpt Protein, Tb927.1.3950 Protein, ANI_1_368094 Protein, AOR_1_284154 Protein, ALAT_1 Protein, ALAAT1 Protein, EHI_159710 Protein, EHI_096750 Protein, LOC5572541 Protein, ALAT Protein, AAT2 Protein, Dpagt1 Protein, LOC100537633 Protein, AlaAT1 Protein

Sujet: This gene encodes cytosolic alanine aminotransaminase 1 (ALT1) also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009].

Poids moléculaire: 54.5 kDa

NCBI Accession: NP_005300