A2ML1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2714611

Détail du produit

Antigène: A2ML1 (alpha-2-Macroglobulin-Like 1 (A2ML1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette A2ML1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Alpha-2-macroglobulin-like 1 (A2ML1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: A2ML1 (alpha-2-Macroglobulin-Like 1 (A2ML1))

Abstract: A2ML1 Produits

Synonymes: CPAMD9 Protein, alpha-2-macroglobulin like 1 Protein, A2ML1 Protein

Sujet: This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 161 kDa

NCBI Accession: NP_653271