PRKAB1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2714672

Détail du produit

Antigène: PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PRKAB1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human AMPK beta-1 chain / AMPKb protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

Autre désignation: Ampk beta-1 Chain,ampkb (PRKAB1 Produits)

Synonymes: AMPK Protein, HAMPKb Protein, 1300015D22Rik Protein, AU021155 Protein, E430008F22 Protein, MGC82489 Protein, prkab1 Protein, wu:fk93d05 Protein, wu:fw87e09 Protein, zgc:56652 Protein, zgc:76975 Protein, zgc:92228 Protein, protein kinase AMP-activated non-catalytic subunit beta 1 Protein, protein kinase, AMP-activated, beta 1 non-catalytic subunit Protein, protein kinase, AMP-activated, beta 1 non-catalytic subunit S homeolog Protein, protein kinase, AMP-activated, beta 1 non-catalytic subunit, b Protein, protein kinase, AMP-activated, beta 1 non-catalytic subunit, a Protein, PRKAB1 Protein, Prkab1 Protein, prkab1.S Protein, prkab1 Protein, prkab1b Protein, prkab1a Protein

Sujet: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). [UniProtKB/Swiss-Prot Function]

Poids moléculaire: 30.2 kDa

NCBI Accession: NP_006244

Pathways: AMPK Signaling, L'effet Warburg