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APOE Protéine
APOE
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
N° du produit ABIN2714831
Détail du produit
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Antigène
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APOE
(Apolipoprotein E (APOE))
Type de proteíne
Recombinant
Origine
Toutes les origines à travers APOE Protéines
Humain
Source
Toutes les sources à travers APOE Protéines
Escherichia coli (E. coli)
Application
Antibody Production (AbP), Standard (STD)
Attributs du produit
Recombinant human Apolipoprotein E / Apo E protein expressed in E. coli. Produced with end-sequenced ORF clone
Pureté
> 90 % as determined by SDS-PAGE and Coomassie blue staining
niveau d'endotoxine
Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
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Information d'application
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Indications d'application
Recombinant human proteins can be used for: Native antigens for optimized antibody production Positive controls in ELISA and other antibody assays
Restrictions
For Research Use only
Stockage
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Buffer
Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
Conseil sur la manipulation
Resuspend the protein in the desired concentration in proper buffer
Stock
-80 °C
Stockage commentaire
Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
Détail du antigène
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Antigène
APOE
(Apolipoprotein E (APOE))
Autre désignation
Apolipoprotein E,apo E (APOE Produits )
Synonymes
ad2 Protein, apoprotein Protein, im:7036787 Protein, wu:fb69a05 Protein, zgc:110064 Protein, apoe Protein, AI255918 Protein, AD2 Protein, LDLCQ5 Protein, LPG Protein, APOEA Protein, Apo-E Protein, apolipoprotein E Protein, apolipoprotein Ea Protein, apoe Protein, apoea Protein, Apoe Protein, APOE Protein
Sujet
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Poids moléculaire
34.3 kDa
NCBI Accession
NP_000032
Pathways
Regulation of Cell Size , Lipid Metabolism
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