ATP2B2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes ATP2B2 Protéines
- ATP2B2 (ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette ATP2B2 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human ATP2B2 / PMCA2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ATP2B2 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- ATP2B2 (ATPase, Ca++ Transporting, Plasma Membrane 2 (ATP2B2))
- Autre désignation
- Atp2b2,pmca2 (ATP2B2 Produits)
- Synonymes
- PMCA2 Protein, PMCA2a Protein, PMCA2i Protein, ATP2B4 Protein, ATP2B2 Protein, PMCA Protein, D6Abb2e Protein, Tmy Protein, dfw Protein, jog Protein, wms Protein, wri Protein, ATPase plasma membrane Ca2+ transporting 2 Protein, ATPase, Ca++ transporting, plasma membrane 2 Protein, ATP2B2 Protein, Atp2b2 Protein, atp2b2 Protein
- Sujet
- The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified.
- Poids moléculaire
- 136.7 kDa
- NCBI Accession
- NP_001001331
- Pathways
- Sensory Perception of Sound, Regulation of Cell Size, Ribonucleoside Biosynthetic Process
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