BCAR3 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes BCAR3 Protéines
- BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
- Type de proteíne
- Recombinant
- Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette BCAR3 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human BCAR3 / SH2D3B protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product BCAR3 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- BCAR3 (Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))
- Autre désignation
- Bcar3,sh2d3b (BCAR3 Produits)
- Synonymes
- NSP2 Protein, SH2D3B Protein, AI131758 Protein, AND-34 Protein, BCAR3 Protein, breast cancer anti-estrogen resistance 3 Protein, breast cancer anti-estrogen resistance 3 L homeolog Protein, BCAR3 Protein, Bcar3 Protein, bcar3 Protein, bcar3.L Protein
- Sujet
- Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
- 92.4 kDa
- NCBI Accession
- NP_003558
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