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BMP10 Protéine

BMP10 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
N° du produit ABIN2715288
  • Antigène Voir toutes BMP10 Protéines
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 4
    • 3
    • 1
    Humain
    Source
    • 5
    • 2
    • 1
    HEK-293 Cells
    Application
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    Specificité
    Optimal preservation of protein structure, post-translational modifications and functions.
    Attributs du produit
    • Recombinant human BMP10 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Pureté
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    niveau d'endotoxine
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 4.0-6.0 ng/ml.
    Top Product
    Discover our top product BMP10 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Restrictions
    For Research Use only
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Conseil sur la manipulation
    Resuspend the protein in the desired concentration in proper buffer
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    Autre désignation
    Bmp10 (BMP10 Produits)
    Synonymes
    BMP10 Protein, si:dkey-13n15.5 Protein, Bmp10 Protein, BMP9 Protein, BMP-10 Protein, bone morphogenetic protein 10 Protein, BMP10 Protein, bmp10 Protein, LOC662386 Protein, Bmp10 Protein
    Sujet
    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation.
    Poids moléculaire
    24.4 kDa
    NCBI Accession
    NP_055297
    Pathways
    Hormone Activity, Regulation of Muscle Cell Differentiation
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