DAXX Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes DAXX Protéines
- DAXX (Death-Domain Associated Protein (DAXX))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette DAXX protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human DAXX (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DAXX Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- DAXX (Death-Domain Associated Protein (DAXX))
- Autre désignation
- Daxx (DAXX Produits)
- Synonymes
- BING2 Protein, DAP6 Protein, EAP1 Protein, LOC100226911 Protein, daxx Protein, si:dz179b20.7 Protein, wu:fd15c03 Protein, death domain associated protein Protein, Fas death domain-associated protein Protein, 28S ribosomal protein S29, mitochondrial Protein, death-domain associated protein Protein, death-associated protein 6 L homeolog Protein, DAXX Protein, Daxx Protein, LOC100226911 Protein, daxx.L Protein, daxx Protein
- Sujet
- This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
- Poids moléculaire
- 81.2 kDa
- NCBI Accession
- NP_001135441
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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