DENND1C Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes DENND1C Protéines
- DENND1C (DENN/MADD Domain Containing 1C (DENND1C))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette DENND1C protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human DENND1C protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DENND1C Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- DENND1C (DENN/MADD Domain Containing 1C (DENND1C))
- Abstract
- DENND1C Produits
- Synonymes
- FAM31C Protein, 4432409M07Rik Protein, DENN/MADD domain containing 1C L homeolog Protein, DENN/MADD domain containing 1C Protein, DENN domain containing 1C Protein, dennd1c.L Protein, DENND1C Protein, Dennd1c Protein
- Sujet
- Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1C, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2 see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010].
- Poids moléculaire
- 86.9 kDa
- NCBI Accession
- NP_079174
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