EIF2AK2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2720058

Détail du produit

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette EIF2AK2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human EIF2AK2 / PKR (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Autre désignation: Eif2ak2,pkr (EIF2AK2 Produits)

Synonymes: PKR Protein, pkr Protein, EIF2AK2 Protein, DKFZp469K1934 Protein, EIF2AK1 Protein, PRKR Protein, 2310047A08Rik Protein, 4732414G15Rik Protein, AI467567 Protein, AI747578 Protein, Pkr Protein, Prkr Protein, Tik Protein, eukaryotic translation initiation factor 2 alpha kinase 2 Protein, eukaryotic translation initiation factor 2-alpha kinase 2 Protein, EIF2AK2 Protein, eif2ak2 Protein, Eif2ak2 Protein

Sujet: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

Poids moléculaire: 61.9 kDa

NCBI Accession: NP_001129123

Pathways: Réparation de l'ADN, ER-Nucleus Signaling, Hepatitis C