PTK2B Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes PTK2B Protéines
- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 4
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette PTK2B protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human FAK2 / PTK2B (transcript variant 4) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PTK2B Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
- Autre désignation
- Fak2,ptk2b (PTK2B Produits)
- Synonymes
- CADTK Protein, CAKB Protein, FADK2 Protein, FAK2 Protein, PKB Protein, PTK Protein, PYK2 Protein, RAFTK Protein, CAKbeta Protein, E430023O05Rik Protein, Raftk Protein, Pyk2 Protein, fak1b Protein, ptk2.2 Protein, ptk2b Protein, si:ch1073-355e8.1 Protein, protein tyrosine kinase 2 beta Protein, PTK2 protein tyrosine kinase 2 beta Protein, protein tyrosine kinase 2aa Protein, PTK2B Protein, Ptk2b Protein, ptk2aa Protein
- Sujet
- This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.
- Poids moléculaire
- 111 kDa
- NCBI Accession
- NP_775267
- Pathways
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling
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