Fibrillarin Protein (FBL) (Myc-DYKDDDDK Tag)

N° du produit ABIN2720913

Détail du produit

Antigène: Fibrillarin (FBL)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Fibrillarin protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human FBL protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Fibrillarin (FBL)

Autre désignation: Fbl (FBL Produits)

Synonymes: FIB Protein, FLRN Protein, RNU3IP1 Protein, wu:fb37g12 Protein, zgc:56145 Protein, zgc:77130 Protein, FBL Protein, AL022665 Protein, CG9888 Protein, Dmel\\CG9888 Protein, Fibri Protein, GCR-6 Protein, GCR6 Protein, Pen59C5 Protein, fib Protein, pen59C5 Protein, MGC76139 Protein, fbl Protein, fibrillarin Protein, Fibrillarin Protein, putative fibrillarin Protein, fibrillarin S homeolog Protein, FBL Protein, fbl Protein, Fbl Protein, Fib Protein, fib1 Protein, LMJF_19_0100 Protein, fbl.S Protein

Sujet: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.

Poids moléculaire: 33.6 kDa

NCBI Accession: NP_001427

Pathways: Ribonucleoside Biosynthetic Process