Fibromodulin Protein (FMOD) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes Fibromodulin (FMOD) Protéines
- Fibromodulin (FMOD)
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Fibromodulin protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human Fibromodulin protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FMOD Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Melanocyte pigmentation inversely correlates with MCP-1 production and angiogenesis-inducing potential." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, (2014) (PubMed).
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Melanocyte pigmentation inversely correlates with MCP-1 production and angiogenesis-inducing potential." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, (2014) (PubMed).
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- Antigène
- Fibromodulin (FMOD)
- Autre désignation
- Fibromodulin (FMOD Produits)
- Synonymes
- FMOD Protein, AI131919 Protein, AU041740 Protein, SLRR2E Protein, LOC100286414 Protein, sc:d0415 Protein, si:dkey-31j12.4 Protein, LOC100229381 Protein, FM Protein, fibromodulin Protein, fibromodulin b Protein, FMOD Protein, Fmod Protein, LOC100286414 Protein, fmodb Protein
- Sujet
- Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.
- Poids moléculaire
- 41.2 kDa
- NCBI Accession
- NP_002014
- Pathways
- Glycosaminoglycan Metabolic Process
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