Fibulin 5 Protein (FBLN5) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes Fibulin 5 (FBLN5) Protéines
- Fibulin 5 (FBLN5)
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Fibulin 5 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human Fibulin-5 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FBLN5 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis." dans: Matrix biology : journal of the International Society for Matrix Biology, Vol. 34, pp. 114-23, (2014) (PubMed).
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LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis." dans: Matrix biology : journal of the International Society for Matrix Biology, Vol. 34, pp. 114-23, (2014) (PubMed).
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- Antigène
- Fibulin 5 (FBLN5)
- Autre désignation
- Fibulin-5 (FBLN5 Produits)
- Synonymes
- zgc:103575 Protein, FBLN5 Protein, MGC108414 Protein, Fibulin-5 Protein, DKFZp469K0327 Protein, ADCL2 Protein, ARCL1A Protein, ARMD3 Protein, DANCE Protein, EVEC Protein, FIBL-5 Protein, UP50 Protein, A55 Protein, fibulin 5 Protein, fbln5 Protein, FBLN5 Protein, Fbln5 Protein
- Sujet
- The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).
- Poids moléculaire
- 47.8 kDa
- NCBI Accession
- NP_006320
- Pathways
- SARS-CoV-2 Protein Interactome
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