Osteoactivin Protein (GPNMB) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes Osteoactivin (GPNMB) Protéines
- Osteoactivin (GPNMB)
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 1
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Osteoactivin protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human GPNMB / HGFIN (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GPNMB Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." dans: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).
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The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." dans: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).
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- Antigène
- Osteoactivin (GPNMB)
- Autre désignation
- Gpnmb,hgfin (GPNMB Produits)
- Synonymes
- HGFIN Protein, NMB Protein, DC-HIL Protein, Dchil Protein, ipd Protein, glycoprotein nmb Protein, glycoprotein (transmembrane) nmb Protein, glycoprotein nmb L homeolog Protein, Gpnmb Protein, GPNMB Protein, gpnmb.L Protein
- Sujet
- The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
- 61.5 kDa
- NCBI Accession
- NP_001005340
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