HDAC4 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes HDAC4 Protéines
- HDAC4 (Histone Deacetylase 4 (HDAC4))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette HDAC4 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human HDAC4 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HDAC4 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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PARP-1 mediates LPS-induced HMGB1 release by macrophages through regulation of HMGB1 acetylation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 12, pp. 6114-23, (2014) (PubMed).
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PARP-1 mediates LPS-induced HMGB1 release by macrophages through regulation of HMGB1 acetylation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 12, pp. 6114-23, (2014) (PubMed).
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- Antigène
- HDAC4 (Histone Deacetylase 4 (HDAC4))
- Autre désignation
- Hdac4 (HDAC4 Produits)
- Synonymes
- CG1770 Protein, DHDAC4 Protein, Dmel\\CG1770 Protein, GC1770 Protein, HDAC Protein, HDAC4a Protein, dHDAC4 Protein, dmHDA405 Protein, hdac4 Protein, dana_GLEANR_19966 Protein, DanaGF18710 Protein, GF18710 Protein, HDAC4 Protein, AHO3 Protein, BDMR Protein, HA6116 Protein, HD4 Protein, HDAC-4 Protein, HDAC-A Protein, HDACA Protein, 4932408F19Rik Protein, AI047285 Protein, wu:fa96d08 Protein, wu:fc56f08 Protein, zgc:152701 Protein, histone deacetylase 4 Protein, hypothetical protein Protein, Histone deacetylase 4 Protein, GF18710 gene product from transcript GF18710-RC Protein, PTRG_03699 Protein, PGTG_15512 Protein, HDAC4 Protein, Dana\GF18710 Protein, Hdac4 Protein, hdac4 Protein
- Sujet
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
- Poids moléculaire
- 118.9 kDa
- NCBI Accession
- NP_006028
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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