HFE Protein (Transcript Variant 6) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes HFE Protéines
- HFE (Hemochromatosis (HFE))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 6
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette HFE protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human HFE / HLAH (transcript variant 6) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HFE Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- HFE (Hemochromatosis (HFE))
- Autre désignation
- Hfe,hlah (HFE Produits)
- Synonymes
- HFE1 Protein, HH Protein, HLA-H Protein, MVCD7 Protein, TFQTL2 Protein, MR2 Protein, hemochromatosis Protein, HFE Protein, Hfe Protein
- Sujet
- The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
- Poids moléculaire
- 36.2 kDa
- NCBI Accession
- NP_620575
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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