IFI16 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2723287

Détail du produit

Antigène: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IFI16 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human IFI16 / IFNGIP1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))

Autre désignation: Ifi16,ifngip1 (IFI16 Produits)

Synonymes: IFNGIP1 Protein, PYHIN2 Protein, IFI16 Protein, Ifitm3l Protein, Ifitml Protein, interferon gamma inducible protein 16 Protein, interferon induced transmembrane protein 2 Protein, myeloid cell nuclear differentiation antigen-like protein Protein, interferon-activable protein 203 Protein, IFI16 Protein, Ifitm2 Protein, LOC100156073 Protein, LOC488622 Protein, Ifi16 Protein

Sujet: This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 81.9 kDa

NCBI Accession: NP_005522

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome