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IL-19 Protein (Transcript Variant 2)

IL19 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, STD, PI Active
N° du produit ABIN2723648
  • Antigène Voir toutes IL-19 (IL19) Protéines
    IL-19 (IL19) (Interleukin 19 (IL19))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    Transcript Variant 2
    Origine
    • 8
    • 4
    • 2
    Humain
    Source
    • 8
    • 3
    • 2
    Escherichia coli (E. coli)
    Application
    Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
    Specificité
    Optimal preservation of protein structure, post-translational modifications and functions.
    Attributs du produit
    • Recombinant human Interleukin-19 / IL19 (transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Pureté
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    niveau d'endotoxine
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Determined by its ability to activate STAT following receptor-ligand interaction.
    Top Product
    Discover our top product IL19 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Restrictions
    For Research Use only
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Conseil sur la manipulation
    Resuspend the protein in the desired concentration in proper buffer
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    IL-19 (IL19) (Interleukin 19 (IL19))
    Autre désignation
    Interleukin-19,il19 (IL19 Produits)
    Synonymes
    IL-10C Protein, MDA1 Protein, NG.1 Protein, ZMDA1 Protein, IL19 Protein, interleukin 19 Protein, IL19 Protein, Il19 Protein
    Sujet
    The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
    Poids moléculaire
    17.9 kDa
    NCBI Accession
    NP_037503
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