IRAK4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes IRAK4 Protéines
- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 2
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IRAK4 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human IRAK4 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IRAK4 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
- Autre désignation
- Irak4 (IRAK4 Produits)
- Synonymes
- zgc:55553 Protein, IRAK4 Protein, ipd1 Protein, irak-4 Protein, ny-ran-64 Protein, ny-ren-64 Protein, ren64 Protein, irak4 Protein, IPD1 Protein, IRAK-4 Protein, NY-REN-64 Protein, REN64 Protein, 8430405M07Rik Protein, 9330209D03Rik Protein, interleukin 1 receptor associated kinase 4 Protein, interleukin-1 receptor-associated kinase 4 Protein, IRAK4 Protein, irak4 Protein, Irak4 Protein
- Sujet
- This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
- 51.3 kDa
- NCBI Accession
- NP_057207
- Pathways
- Signalisation NF-kappaB, Signalisation TLR, Activation of Innate immune Response, Toll-Like Receptors Cascades
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