IRF4 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes IRF4 Protéines
- IRF4 (Interferon Regulatory Factor 4 (IRF4))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IRF4 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human IRF4 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IRF4 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- IRF4 (Interferon Regulatory Factor 4 (IRF4))
- Autre désignation
- Irf4 (IRF4 Produits)
- Synonymes
- LSIRF Protein, MUM1 Protein, NF-EM5 Protein, AI385587 Protein, IRF-4 Protein, Spip Protein, IRF4 Protein, si:ch73-170d1.2 Protein, irf4 Protein, interferon regulatory factor 4 Protein, interferon regulatory factor 4a Protein, Interferon regulatory factor 4 Protein, PWWP domain-containing protein MUM1 Protein, IRF4 Protein, Irf4 Protein, irf4a Protein, irf4 Protein, LOC612320 Protein, LOC100068881 Protein
- Sujet
- The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(614)(p25q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
- Poids moléculaire
- 51.6 kDa
- NCBI Accession
- NP_002451
- Pathways
- Chromatin Binding
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