IDH2 Protein (DYKDDDDK Tag)
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- Antigène Voir toutes IDH2 Protéines
- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Insect cells (Sf9)
- Purification/Conjugué
- Cette IDH2 protéine est marqué à la DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human Isocitrate dehydrogenase / IDH2 (C-term DDK tag) protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IDH2 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
- Autre désignation
- Isocitrate Dehydrogenase,idh2 (IDH2 Produits)
- Synonymes
- F6P23.14 Protein, F6P23_14 Protein, IDH-II Protein, NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 2 Protein, isocitrate dehydrogenase II Protein, isocitrate dehydrogenase subunit 2 Protein, D2HGA2 Protein, ICD-M Protein, IDH Protein, IDHM Protein, IDP Protein, IDPM Protein, mNADP-IDH Protein, E430004F23 Protein, IDPm Protein, Idh-2 Protein, wu:fb33c06 Protein, wu:fk31e05 Protein, wu:fq43b01 Protein, zgc:55485 Protein, idh2 Protein, IDH2 Protein, isocitrate dehydrogenase subunit 2 Protein, isocitrate dehydrogenase (NADP(+)) 2, mitochondrial Protein, isocitrate dehydrogenase 2 (NADP+), mitochondrial Protein, isocitrate dehydrogenase 2 (NADP+), mitochondrial S homeolog Protein, isocitrate dehydrogenase [NADP], mitochondrial Protein, IDH2 Protein, Idh2 Protein, idh2.S Protein, idh2 Protein, LOC100441867 Protein
- Sujet
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
- Poids moléculaire
- 46.6 kDa
- NCBI Accession
- NP_002159
- Pathways
- L'effet Warburg
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