LMAN1 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes LMAN1 Protéines
- LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
- Type de proteíne
- Recombinant
- Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette LMAN1 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human LMAN1 / ERGIC53 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product LMAN1 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))
- Autre désignation
- Lman1,ergic53 (LMAN1 Produits)
- Synonymes
- ERGIC-53 Protein, ERGIC53 Protein, F5F8D Protein, FMFD1 Protein, MCFD1 Protein, MR60 Protein, gp58 Protein, 2610020P13Rik Protein, AI326273 Protein, AU043785 Protein, C730041J05 Protein, P58 Protein, p58 Protein, LMAN1 Protein, cpx-iii Protein, cpxiii Protein, lman1 Protein, wu:fc54c09 Protein, wu:fi36e01 Protein, Xp58 Protein, lman1-a Protein, lectin, mannose binding 1 Protein, lectin, mannose-binding, 1 Protein, complexin 3 Protein, lectin, mannose binding 1 S homeolog Protein, LMAN1 Protein, Lman1 Protein, cplx3 Protein, lman1 Protein, lman1.S Protein
- Sujet
- The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH -sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency.
- Poids moléculaire
- 54.2 kDa
- NCBI Accession
- NP_005561
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