MCM3 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes MCM3 Protéines
- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette MCM3 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human MCM3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MCM3 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
- Autre désignation
- Mcm3 (MCM3 Produits)
- Synonymes
- HCC5 Protein, P1-MCM3 Protein, P1.h Protein, RLFB Protein, AL033361 Protein, C80350 Protein, Mcmd Protein, P1 Protein, p1.m Protein, cb32 Protein, chunp6867 Protein, wu:fa26g03 Protein, CG4206 Protein, DmMCM3 Protein, DmMcm3 Protein, DmeMCM3 Protein, Dmel\\CG4206 Protein, MCM3 Protein, McM3 Protein, Mcp-PCR2 Protein, PCR2 Protein, dMCM3 Protein, xmcm3 Protein, minichromosome maintenance complex component 3 Protein, MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) Protein, Minichromosome maintenance 3 Protein, minichromosome maintenance complex component 3 L homeolog Protein, MCM complex subunit Mcm3 Protein, MCM3 Protein, mcm3 Protein, Mcm3 Protein, mcm3.L Protein
- Sujet
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
- Poids moléculaire
- 90.8 kDa
- NCBI Accession
- NP_002379
- Pathways
- Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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