Melanoma gp100 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes Melanoma gp100 (PMEL) Protéines
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Type de proteíne
- Recombinant
- Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Melanoma gp100 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human Melanoma gp100 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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Premelanosome Protein (PMEL) (AA 25-467) protein (His-SUMO Tag)PMEL Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
Premelanosome Protein (PMEL) (AA 25-467) protein (His tag)PMEL Origine: Humain Hôte: Levure Recombinant > 90 % SDS
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
- Autre désignation
- Melanoma Gp100 (PMEL Produits)
- Sujet
- This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants.
- Poids moléculaire
- 70.1 kDa
- NCBI Accession
- NP_008859
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